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Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with phentermine and topiramate and each time you refill your prescription.

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Activation of the PPAR-γ subtype is known to increase insulin sensitization, modulate glucose and lipid metabolism.

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As with all insulins, use caution in patients with hypoglycemia unawareness and in patients who may be predisposed to hypoglycemia (e.

Although the incidence of serious heart failure was increased with pioglitazone versus placebo in the total PROactive population of patients with type 2 diabetes and macrovascular disease, subsequent mortality or morbidity was not increased in patients with serious heart failure.

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Six of these nine patients continued to receive pioglitazone hydrochloride, two patients were noted to have the CPK elevation on the last day of dosing and one patient discontinued pioglitazone hydrochloride due to the elevation.

Risk of Cardiovascular Disease in Patients with Nonalcoholic Fatty Liver Disease.

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The adverse reaction profile was similar to that of patients treated with placebo.

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Several intervention trials using antihypertensive agents, lipid-modifying drugs (principally statins), glucose-lowering agents, or multifactorial intervention strategies have looked at macrovascular outcomes in patients with type 2 diabetes.

If any of these occur, check your blood sugar closely and tell your doctor right away.

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In 2013 the FDA approved the drug in three formulations: As a stand-alone with the brand-name Nesina.

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The syndrome historically known as maturity onset diabetes of youth (MODY), which is now understood to be a variety of defects in beta-cell function, accounts for 2-5% of individuals with type 2 diabetes who present at a young age and have mild disease.

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The funding sources had no role in the design, analysis, and interpretation of the results, and thus the authors were independent from the funding source.

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Effectiveness of Ipragliflozin, a Sodium-Glucose Co-transporter 2 Inhibitor, as a Second-line Treatment for Non-Alcoholic Fatty Liver Disease Patients with Type 2 Diabetes Mellitus Who Do Not Respond to Incretin-Based Therapies Including Glucagon-like Peptide-1 Analogs and Dipeptidyl Peptidase-4 Inhibitors.

Why we need easy access to all data from all clinical trials and how to accomplish it.

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Invokana is a prescription medicine used along with diet and exercise to lower blood sugar in adults with type 2 diabetes.

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INVOKANA may affect the way other medicines work, and other medicines may affect how INVOKANA works.

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To report SUSPECTED ADVERSE REACTIONS, contact Takeda Pharmaceuticals at 1-877-825-3327 or FDA at 1-800-FDA-1088 or www.

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The matter is that a manufacturer can not possess a patent for a certain chemical agent, this is why different manufacturers of generic drugs are able to produce the so-called generics legally.

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